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Bioinformatics Advance Access published online on May 18, 2006

Bioinformatics, doi:10.1093/bioinformatics/btl195
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© The Author (2006). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received March 29, 2006
Revised May 10, 2006
Accepted May 15, 2006

Article

A model diagram layout extension for SBML

Ralph Gauges 1 *, Ursula Rost 1, Sven Sahle 1, and Katja Wegner 1

1 Bioinformatics and Computational Biochemistry, EML Research, Schloss-Wolfsbrunnen Weg 33, D-69118 Heidelberg, Germany

* To whom correspondence should be addressed.
Ralph Gauges, E-mail: Ralph.Gauges{at}eml-r.villa-bosch.de


   Abstract

Motivation: Since the knowledge about processes in living cells is increasing, modeling and simulation techniques are used to get new insights into these complex processes. During the last few years, the SBML file format has gained in popularity and support as a means of exchanging model data between the different modeling and simulation tools. In addition to specifying the model as a set of equations, many modern modeling tools allow the user to create and interact with the model in the form of a reaction graph. Unfortunately, the SBML file format does not provide for the storage of this graph data along with the mathematical description of the model.

Results: Therefore, we developed an extension to the SBML file format that makes it possible to store such layout information which describes position and size of objects in the graphical representation.

Availability: The complete specification can be found on [1]. Additionally, a complete implementation exists as part of libSBML [2].


Associate Editor: Martin Bishop
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