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Bioinformatics Advance Access published online on June 16, 2006

Bioinformatics, doi:10.1093/bioinformatics/btl288
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© The Author (2006). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received April 25, 2006
Accepted May 26, 2006

Discovery note

Building chromosome-wide LD maps

María M. Abad-Grau 1, Rosana Montes 1, and Paola Sebastiani 2 *

1 Software Engineering Department, University of Granada, Granada 18071 Spain
2 Department of Biostatistics, Boston University School of Public Health, Boston MA 02118

* To whom correspondence should be addressed.
Paola Sebastiani, E-mail: sebas{at}bu.edu


   Abstract

Summary: BMapBuilder builds maps of pairwise linkage disequilibrium (LD) in either two or three dimensions. The optimized resolution allows for graphical display of LD for single nucleotide polymorphisms (SNPs) in a whole chromosome.

Availability: The program is coded in Java, which runs on all relevant operating systems, including Windows, Mac and Unix/Linux, and is available from http://bios.ugr.es/BMapBuilder.

Supplementary information: Maps displaying chomosome-wide LD are available at http://bios.ugr.es/BMapBuilder/supplementary.


Associate Editor: Martin Bishop
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