Skip Navigation



Bioinformatics Advance Access published online on June 20, 2006
Bioinformatics, doi:10.1093/bioinformatics/btl331
This Article
Right arrow Advance Access manuscript (PDF) Freely available
Right arrow All Versions of this Article:
22/16/2053    most recent
btl331v1
Right arrow Comments: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Comments are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Hong, S.-E.
Right arrow Articles by Kim, D. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hong, S.-E.
Right arrow Articles by Kim, D. H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author (2006). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received April 12, 2006
Revised June 7, 2006
Accepted June 9, 2006

Applications note

HCNet: a database of heart and calcium functional network

Seong-Eui Hong 1 {dagger}, Seong-Hwan Rho 1 {dagger}, Young I. L. Yeom 2, and Do Han Kim 1 *

1 Department of Life Science, Gwangju Institute of Science and Technology, 1 Oryong-dong, Buk-gu, Gwangju 500-712, Korea
2 Laboratory of Human Genomics, Korea Research Institute of Bioscience and Biotechnology, Deajeon, Korea

* To whom correspondence should be addressed.
Do Han Kim, E-mail: dhkim{at}gist.ac.kr


  Abstract

Summary: The Heart and Calcium functional Network (HCNet) database is a collection of functional gene modules calculated from the microarray data compendium available from the GEO database. It is a specialized database designed to assist experimentalists for cardiac calcium signaling research by providing the pre-calculated gene clusters and their potential correlation network in heart.

In the current release of HCNet, 57 functional modules from 786 target genes obtained by a biclustering analysis of 381 microarray datasets are available. Detailed information of the clusters such as expression profiles, network diagrams is provided in two categories, heart-specific genes and heart-specific genes along with calcium toolkit genes. Overrepresented gene ontological categories and transcription factors in each cluster are also provided to infer the biological implications of the detected functional modules.

Availability: HCNet is available at http://sbrg2.gist.ac.kr/hcnet.

Associate Editor: Golan Yona

{dagger}These authors contributed equally to this work.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Physiol. GenomicsHome page
U. D. Akavia and D. Benayahu
Meta-analysis and profiling of cardiac expression modules
Physiol Genomics, November 12, 2008; 35(3): 305 - 315.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.