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Bioinformatics Advance Access published online on July 4, 2006
Bioinformatics, doi:10.1093/bioinformatics/btl358
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© The Author (2006). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received March 12, 2006
Revised May 26, 2006
Accepted June 24, 2006

Applications note

ZooDDD: a cross-species database for digital differential display analysis

Yun-Ching Chen 1 *, Chung-Der Hsiao 2 *, Wen-Dar Lin 1, Chung-Ming Hu 1, Pung-Pung Hwang 2, and Jan-Ming Ho 1 *

1 Institute of Information Science, Academia Sinica, NanKang 115, Taipei, Taiwan, ROC
2 Institute of Cellular and Organismic Biology, Academia Sinica, NanKang 115, Taipei, Taiwan, ROC

* To whom correspondence should be addressed.
Jan-Ming Ho, E-mail: hoho{at}iis.sinica.edu.tw


  Abstract

Summary: In this paper, we combined EST information from the UniGene database and orthologous relationships from the Ensembl database to construct a ZooDDD database. The primary function of ZooDDD is to mine evolutionary conserved, highly expressed, tissue-specific orthologues in model animals. The candidate genes of interest derived from the ZooDDD database will provide biologists with a good step for comparing the expression, functions, and evolution of animal genomes.

Availability: http://bio301.iis.sinica.edu.tw/~ZooDDDNew/main.php.

Associate Editor: Nikolaus Rajewsky

* These authors contributed equally to this work.


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