Skip Navigation



Bioinformatics Advance Access published online on July 28, 2006
Bioinformatics, doi:10.1093/bioinformatics/btl413
This Article
Right arrow Advance Access manuscript (PDF) Freely available
Right arrow All Versions of this Article:
22/20/2574    most recent
btl413v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Gariev, I. A.
Right arrow Articles by Varfolomeev, S. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gariev, I. A.
Right arrow Articles by Varfolomeev, S. D.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author (2006). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received March 13, 2006
Revised July 7, 2006
Accepted July 25, 2006

Applications note

Hierarchical classification of hydrolases catalytic sites

Igor A. Gariev 1 * and Sergey D. Varfolomeev 1

1 School of Enzymology, Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, 119992, Russia

* To whom correspondence should be addressed.
Igor A. Gariev, E-mail: gariev{at}hotmail.com


  Abstract

Summary: Universal ontology of catalytic sites is required to systematize enzyme catalytic sites, their evolution, as well as relations between catalytic sites and protein families, organisms and chemical reactions. Here we present a classification of hydrolases catalytic sites based on hierarchical organization. The Web-accessible database provides information on the catalytic sites, protein folds, EC numbers and source organisms of the enzymes and includes software allowing for analysis and visualization of the relations between them.

Availability: http://www.enzyme.chem.msu.ru/hcs/.

Associate Editor: Charlie Hodgman
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.