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Bioinformatics Advance Access published online on July 31, 2006
Bioinformatics, doi:10.1093/bioinformatics/btl422
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© The Author (2006). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received April 26, 2006
Revised July 12, 2006
Accepted July 28, 2006

Applications note

Sebida: a database for the functional and evolutionary analysis of genes with sex-biased expression

Florian Gnad 1 * and John Parsch 2

1 Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany
2 Department of Biology, University of Munich (LMU), Grosshaderner Str. 2, 82152 Planegg-Martinsried, Germany

* To whom correspondence should be addressed.
Florian Gnad, E-mail: gnad{at}biochem.mpg.de


  Abstract

Summary: We describe Sebida, a database of genes with sex-biased expression. The database integrates results from multiple, independent microarray studies comparing male and female gene expression in Drosophila melanogaster, Drosophila simulans, and Anopheles gambiae. Sebida uses standard nomenclature, which allows individual genes to be compared across different microarray platforms and to be queried by gene name, symbol, or annotation number. In addition to ratios of male/female expression for each gene, Sebida also contains information useful for evolutionary studies, such as local recombination rate, degree of codon bias, and interspecific divergence at synonymous and nonsynonymous sites.

Availability: Sebida can be accessed at http://www.sebida.de.

Associate Editor: Alvis Brazma
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