Skip Navigation



Bioinformatics Advance Access published online on August 29, 2006
Bioinformatics, doi:10.1093/bioinformatics/btl456
This Article
Right arrow Advance Access manuscript (PDF) Freely available
Right arrowOA All Versions of this Article:
22/21/2709    most recent
btl456v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Google Scholar
Right arrow Articles by Ulrich, M.
Right arrow Articles by Eils, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ulrich, M.
Right arrow Articles by Eils, R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2006 The Author(s)
Received June 11, 2006
Revised August 15, 2006
Accepted August 19, 2006

Applications note

Tropical - parameter estimation and simulation of reaction-diffusion models based on spatio-temporal microscopy images

Markus Ulrich 1 {dagger}, Constantin Kappel 1 {dagger}, Joel Beaudouin 1, Stefan Hezel 1, Jochen Ulrich 1, and Roland Eils 2 *

1 Department of Theoretical Bioinformatics, German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg
2 Department of Theoretical Bioinformatics, German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg; Institute for Pharmacy and Molecular Biology, University of Heidelberg, Im Neuenheimer Feld 364, 69120 Heidelberg

* To whom correspondence should be addressed.
Roland Eils, E-mail: r.eils{at}dkfz.de


  Abstract

Summary: Tropical is a software for simulation and parameter estimation of reaction-diffusion models. Based on spatio-temporal microscopy images, Tropical estimates reaction and diffusion coefficients for user-defined models. Tropical allows the investigation of systems with an inhomogeneous distribution of molecules, making it well suited for quantitative analyses of microscopy experiments such as fluorescence recovery after photobleaching (FRAP).

Availability: Tropical is available free of charge for academic use at http://www.dkfz.de/tbi/projects/modellingAndSimulationOfCelluarSystems/tropical.jsp after signing a material transfer agreement.

Supplementary information: http://www.dkfz.de/tbi/projects/modellingAndSimulationOfCelluarSystems/tropical.jsp.

Associate Editor: Alfonso Valencia

{dagger} The authors contributed equally to this work.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.