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Bioinformatics Advance Access published online on December 4, 2006
Bioinformatics, doi:10.1093/bioinformatics/btl618
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© The Author (2006). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received September 20, 2006
Revised November 29, 2006
Accepted November 29, 2006

Applications note

AutoGRAPH: an interactive web server for automating and visualizing comparative genome maps

Thomas Derrien 1, Catherine André 1, Francis Galibert 1, and Christophe Hitte 1 *

1 CNRS UMR6061 Génétique et Développement, Université de Rennes1, IFR140, 2 Av du Pr. Léon Bernard, CS 34317, 35043 France

* To whom correspondence should be addressed.
Christophe Hitte, E-mail: hitte{at}univ-rennes1.fr


  Abstract

AutoGRAPH is an interactive web server for automatic multi-species comparative genomics analyses based on personal datasets or pre-inserted public datasets. This program automatically identifies conserved segments and breakpoint regions, assesses the conservation of marker/gene order between organisms, constructs synteny maps for two to three species and generates high-quality, interactive displays facilitating the identification of chromosomal rearrangements. AutoGRAPH can also be used for the integration and comparison of several types of genomic resources (meiotic maps, radiation hybrid maps, genome sequences) for a single species, making AutoGRAPH a versatile tool for comparative genomics analysis.

Availability: http://genoweb.univ-rennes1.fr/tom_dog/AutoGRAPH/.

Supplementary information: A description of the algorithm and additional information are available at http://genoweb.univ-rennes1.fr/tom_dog/AutoGRAPH/Tutorial.php.

Associate Editor: Alfonso Valencia
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