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Bioinformatics Advance Access published online on January 31, 2007
Bioinformatics, doi:10.1093/bioinformatics/btm027
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© The Author (2007). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

COPYCAT: Co-phylogenetic Analysis tool

Jan P. Meier-Kolthoff 1, Alexander F. Auch 1,*, Daniel H. Huson 1 and Markus Göker 2

1Center for Bioinformatics (ZBIT), Sand 14, Tübingen, University of Tübingen, Germany,
2Organismic Botany/Mycology, Auf der Morgenstelle 1, Tübingen, University of Tübingen, Germany

*to whom correspondence should be addressed. Alexander Auch, E-mail: auch{at}informatik.uni-tuebingen.de


  Abstract

Summary: We have developed the software COPYCAT which provides an easy and fast access to cophylogenetic analyses.It incorporates a wrapper for the program PARAFIT, which conducts a statistical test for the presence of congruence between host and parasite phylogenies. COPYCAT offers various features, such as the creation of customized host-parasite association data and the computation of phylogenetic host/parasite trees based on the NCBI taxonomy.

Availability: COPYCAT and its manual are freely available at http://www-ab.informatik.uni-tuebingen.de/software/copycat.

Supplementary information: Results of the real-world example can be found at http://www-ab.informatik.uni-tuebingen.de/software/copycat or Bioinformatics online.

Associate Editor: Keith Crandall

Received on November 28, 2006; revised on January 19, 2007; accepted on January 23, 2007

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