Bioinformatics Advance Access published online on September 10, 2007
Bioinformatics, doi:10.1093/bioinformatics/btm404
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ClustalW and ClustalX version 2.0
1The Conway Institute of Biomolecular and Biomedical ResearHch, University College Dublin, Belfield, Dublin 4, Ireland.
2Laboratoire de Biologie et Genomique Structurales, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.
3European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
4EMBL Outstation-European Bioinformatics Institute, Wellcome Trust Genome Campus Hinxton, Cambridge, CB10 1SD, UK
*To whom correspondence should be addressed. mark larkin, E-mail: mark.larkin{at}ucd.ie
| Abstract |
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Motivation: The ClustalW and ClustalX multiple sequence alignment programs have been completely rewritten in C++. This will facilitate the further development of the alignment algorithms in the future and has allowed proper porting of the programs to the latest versions of Linux, Macintosh and Windows operating sys-tems.
Availability: The programs can be run on-line from the EBI web server: http://www.ebi.ac.uk/ols/toclustalw2The source code and executables for Windows, Linux and Macin-tosh computers are available from the EBI ftp site ftp://ftp.ebi.ac.uk/pub/software/clustalw2/
Contact: clustalw{at}ucd.ie
Associate Editor: Dr. Alex Bateman
Received on June 27, 2007; revised on August 3, 2007; accepted on August 3, 2007
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L. Malki, M. Yanku, I. Borovok, G. Cohen, M. Mevarech, and Y. Aharonowitz Identification and Characterization of gshA, a Gene Encoding the Glutamate-Cysteine Ligase in the Halophilic Archaeon Haloferax volcanii J. Bacteriol., August 15, 2009; 191(16): 5196 - 5204. [Abstract] [Full Text] [PDF] |
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J. Gury, H. Seraut, N. P. Tran, L. Barthelmebs, S. Weidmann, P. Gervais, and J.-F. Cavin Inactivation of PadR, the Repressor of the Phenolic Acid Stress Response, by Molecular Interaction with Usp1, a Universal Stress Protein from Lactobacillus plantarum, in Escherichia coli Appl. Envir. Microbiol., August 15, 2009; 75(16): 5273 - 5283. [Abstract] [Full Text] [PDF] |
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J. L. Burns and T. J. DiChristina Anaerobic Respiration of Elemental Sulfur and Thiosulfate by Shewanella oneidensis MR-1 Requires psrA, a Homolog of the phsA Gene of Salmonella enterica Serovar Typhimurium LT2 Appl. Envir. Microbiol., August 15, 2009; 75(16): 5209 - 5217. [Abstract] [Full Text] [PDF] |
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Z. Zhang, X. Zhu, L. M. Stevens, and D. Stein Distinct functional specificities are associated with protein isoforms encoded by the Drosophila dorsal-ventral patterning gene pipe Development, August 15, 2009; 136(16): 2779 - 2789. [Abstract] [Full Text] [PDF] |
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C. P. Walsh, A. Davies, A. J. Butcher, A. C. Dolphin, and A. Kitmitto Three-dimensional Structure of CaV3.1: COMPARISON WITH THE CARDIAC L-TYPE VOLTAGE-GATED CALCIUM CHANNEL MONOMER ARCHITECTURE J. Biol. Chem., August 14, 2009; 284(33): 22310 - 22321. [Abstract] [Full Text] [PDF] |
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A. Reymer, K. Frykholm, K. Morimatsu, M. Takahashi, and B. Norden From the Cover: Structure of human Rad51 protein filament from molecular modeling and site-specific linear dichroism spectroscopy PNAS, August 11, 2009; 106(32): 13248 - 13253. [Abstract] [Full Text] [PDF] |
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Q. H. Christensen and J. E. Cronan The Thermoplasma acidophilum LplA-LplB Complex Defines a New Class of Bipartite Lipoate-protein Ligases J. Biol. Chem., August 7, 2009; 284(32): 21317 - 21326. [Abstract] [Full Text] [PDF] |
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S. K. Krueger, M. C. Henderson, L. K. Siddens, J. E. VanDyke, A. D. Benninghoff, P. A. Karplus, B. Furnes, D. Schlenk, and D. E. Williams Characterization of Sulfoxygenation and Structural Implications of Human Flavin-Containing Monooxygenase Isoform 2 (FMO2.1) Variants S195L and N413K Drug Metab. Dispos., August 1, 2009; 37(8): 1785 - 1791. [Abstract] [Full Text] [PDF] |
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M. J. Lace, C. Isacson, J. R. Anson, A. T. Lorincz, S. P. Wilczynski, T. H. Haugen, and L. P. Turek Upstream Regulatory Region Alterations Found in Human Papillomavirus Type 16 (HPV-16) Isolates from Cervical Carcinomas Increase Transcription, ori Function, and HPV Immortalization Capacity in Culture J. Virol., August 1, 2009; 83(15): 7457 - 7466. [Abstract] [Full Text] [PDF] |
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K. E. Varley, D. G. Mutch, T. B. Edmonston, P. J. Goodfellow, and R. D. Mitra Intra-tumor heterogeneity of MLH1 promoter methylation revealed by deep single molecule bisulfite sequencing Nucleic Acids Res., August 1, 2009; 37(14): 4603 - 4612. [Abstract] [Full Text] [PDF] |
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S. Spork, J. A. Hiss, K. Mandel, M. Sommer, T. W. A. Kooij, T. Chu, G. Schneider, U. G. Maier, and J. M. Przyborski An Unusual ERAD-Like Complex Is Targeted to the Apicoplast of Plasmodium falciparum Eukaryot. Cell, August 1, 2009; 8(8): 1134 - 1145. [Abstract] [Full Text] [PDF] |
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R. Lucking, J. D. Lawrey, M. Sikaroodi, P. M. Gillevet, J. L. Chaves, H. J. M. Sipman, and F. Bungartz Do lichens domesticate photobionts like farmers domesticate crops? Evidence from a previously unrecognized lineage of filamentous cyanobacteria Am. J. Botany, August 1, 2009; 96(8): 1409 - 1418. [Abstract] [Full Text] [PDF] |
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