Skip Navigation



Bioinformatics Advance Access published online on September 14, 2007
Bioinformatics, doi:10.1093/bioinformatics/btm458
This Article
Right arrow Advance Access manuscript (PDF)
Right arrow All Versions of this Article:
23/22/3105    most recent
btm458v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Miao-Xin, L.
Right arrow Articles by C., S. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Miao-Xin, L.
Right arrow Articles by C., S. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author (2007). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

IGG: A Tool to Integrate GeneChips for Genetic Studies

Li Miao-Xin 1, Jiang Lin 6, Ho S.L. 4, Song You-Qiang 1,4,* and Sham Pak C. 2,4,5

Department of 1Biochemistry, 2Psychiatry and 3Medicine, 4the Centre for Reproduction, Development and Growth, and 5Genome Research Center, The University of Hong Kong, Pokfulam, Hong Kong and 6Hunan Business College, Changsha, Hunan 410205, China

*To whom correspondence should be addressed. Dr.Youqiang Song , E-mail: songy{at}hkucc.hku.hk


  Abstract

To facilitate genetic studies using high throughput genotyping technologies, we have developed an open source tool to integrate genotype data across the Affymetrix and Illumina platforms. It can efficiently integrate a large amount of data from various GeneChips, add genotypes of the HapMap Project into a specific project, flexibly trim and export the integrated data with different formats of popular genetic analysis tools, and highly control the quality of genotype data. Furthermore, this tool has sufficiently simplified its usage through its user-friendly graphic interface and is independent of third-party databases. IGG has successfully been applied to a genome-wide linkage scan in a Charcot-Marie-Tooth disease pedigree by integrating three types of GeneChips and HapMap project genotypes.

Availability: http://bioinfo.hku.hk/iggweb (version 0.9).

Contacts: limx54{at}yahoo.com

Associate Editor: Prof. Martin Bishop

Received on June 22, 2007; revised on August 10, 2007; accepted on September 3, 2007

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.