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Bioinformatics Advance Access published online on September 25, 2007
Bioinformatics, doi:10.1093/bioinformatics/btm462
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© The Author (2007). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

CellMontage: Similar Expression Profile Search Server

Wataru Fujibuchi a, Larisa Kiseleva a, Takeaki Taniguchi b, Hajime Harada a and Paul Horton *,a

aComputational Biology Research Center, AIST Waterfront Bio-IT Research Bldg., 2-42 Aomi Koto-ku, Tokyo 135-0064 and bMitsubishi Research Institute, Inc., 3-6, Otemachi 2-chome Chiyoda-ku, Tokyo 100-8141

*To whom correspondence should be addressed. Dr. Paul Horton E-mail: horton-p{at}aist.go.jp


  Abstract

Summary: The establishment and rapid expansion of microarray databases has created a need for new search tools. Here we present CellMontage, the first server for expression profile similarity search over a large database — 69,000 microarray experiments derived from NCBI's GEO site. CellMontage provides a novel, content based search engine for accessing gene expression data. Microarray experiments with similar overall expression to a user provided expression profile (e.g. microarray experiment) are computed and displayed — usually within 20 seconds. The core search engine software is downloadable from the site.

Supplementary material: http://cellmontage.cbrc.jp/supplementary/

Availability: http://cellmontage.cbrc.jp/

Contact: w.fujibuchi{at}aist.go.jp (general) horton-p{at}aist.go.jp (search engine software)

Associate Editor: Prof. Martin Bishop

Received on July 17, 2007; revised on August 17, 2007; accepted on September 6, 2007

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