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Bioinformatics Advance Access published online on January 17, 2008
Bioinformatics, doi:10.1093/bioinformatics/btm494
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© The Author (2008). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations

Jian Yang 1, Chengcheng Hu 2, Han Hu 1, Rongdong Yu 2, Zhen Xia 1, Xiuzi Ye 2 and Jun Zhu 1,*

1Institute of Bioinformatics, Zhejiang University, Hangzhou, China, 310029 and 2Computer Graphics and Imaging Laboratory, Zhejiang University, Hangzhou, China, 310027

*To whom correspondence should be addressed. Dr. Jun Zhu, E-mail: jzhu{at}zju.edu.cn


  Abstract

Summary: QTLNetwork is a software package for mapping and visualizing the genetic architecture underlying complex traits for experimental populations derived from a cross between two inbred lines. It can simultaneously map QTLs with individual effects, epistasis, and QTL-environment interaction. Currently, it is able to handle data from F2, backcross, recombinant inbred lines and double-haploid populations, as well as populations from specific mating designs (immortalized F2 and BCnFm populations). The Windows version of QTLNetwork was developed with a graphic user interface. And also, the command-line versions have the facility to be run in other prevalent operating systems, such as Linux, Unix and MacOS.

Availability: http://ibi.zju.edu.cn/software/qtlnetwork/index.htm

Contact: jzhu{at}zju.edu.cn

Associate Editor: Prof. Keith Crandll

Received on August 26, 2007; revised on August 26, 2007; accepted on September 25, 2007

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