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Bioinformatics Advance Access published online on December 1, 2007
Bioinformatics, doi:10.1093/bioinformatics/btm599
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© The Author (2007). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

COMPARE, a multi-organism system for cross-species data comparison and transfer of information.

David Salgado 1,{dagger}, Gregory Gimenez 1,{dagger}, François Coulier 2 and Christophe Marcelle 1,*

1Developmental Biology Institute of Marseille Luminy (IBDML). CNRS UMR 6216. Université de la Méditerranée. Campus de Luminy, case 907. 13288 Marseille
2Laboratory of Molecular Oncology, Marseille Cancer Institute, UMR599, 27 Bd. Leï Roure, 13009 Marseille, France.

*To whom correspondence should be addressed. Prof. Christophe Marcelle, E-mail: myobasecompare{at}ibdm.univ-mrs.fr


  Abstract

Motivation: COMPARE is a multi-organism web-based resource system designed to easily retrieve, correlate and interpret data across species. The COMPARE interface provides access to a wide array of information including genomic structure, expression data, annotations, pathways, and literature links for human and three widely studied animal models (zebrafish, Drosophila, and mouse). A consensus ortholog-finding pipeline combining several ortholog prediction methods allows accurate comparisons of data across species and has been utilized to transfer information from well studied organisms to more poorly annotated ones.

Availability: http://compare.ibdml.univ-mrs.fr

Contact: myobasecompare{at}ibdm.univ-mrs.fr

Associate Editor: Prof. John Quackenbush

{dagger}Joint first authors.

Received on August 13, 2007; revised on November 15, 2007; accepted on November 28, 2007

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