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Bioinformatics Advance Access published online on January 24, 2008
Bioinformatics, doi:10.1093/bioinformatics/btn020
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© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

A Discrete View on Fold Space

Manfred J. Sippl *, Stefan J. Suhrer , Markus Gruber and Markus Wiederstein

*To whom correspondence should be addressed. Manfred Sippl, E-mail: sippl{at}came.sbg.ac.at


  Abstract

Summary: The data base of known protein structures contains an overwhelming number of structural similarities that frequently point to intriguing biological relationships. The similarities are often difficult to spot and once detected their comprehension needs proper visualization. Here we introduce the new concept of a fold space navigator, a user interface enabling the efficient navigation through fold space and the instantaneous visualization of pairwise structure similarities.

Availability: The Fold Space Navigator is accessible as a public web service at http://services.came.sbg.ac.at.

Contact: sippl{at}came.sbg.ac.at

Associate Editor: Burkhard Rost

Received on December 21, 2007; revised on January 10, 2008; accepted on January 10, 2008

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