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Bioinformatics Advance Access published online on January 19, 2008
Bioinformatics, doi:10.1093/bioinformatics/btn026
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© The Author (2008). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

GENESIS: Genome Evolution Scenarios

Simon Gog , Martin Bader and Enno Ohlebusch

Institute of Theoretical Computer Science, University of Ulm, D-89069 Ulm, Germany

To whom correspondence should be addressed. Simon Gog, E-mail: simon.gog{at}uni-ulm.de


  Abstract

Summary: We implemented a software tool called GENESIS for three different genome rearrangement problems: Sorting a unichromosomal genome by weighted reversals and transpositions (SwRT), sorting a multichromosomal genome by reversals, translocations, fusions, and fissions (SRTl), and sorting a multichromosomal genome by weighted reversals, translocations, fusions, fissions, and transpositions (SwRTTl).

Availability: Source code can be obtained by the authors, or use the web interface http://www.uni-ulm.de/in/theo/research/genesis.html.

Contact: martin.bader{at}uni-ulm.de, simon.gog{at}uni-ulm.de, enno.ohlebusch{at}uni-ulm.de

Associate Editor: Dr. Chris Stoeckert

Received on November 23, 2007; revised on January 14, 2008; accepted on January 14, 2008

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