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Bioinformatics Advance Access first published online on January 28, 2008
This version published online on February 25, 2008
Bioinformatics, doi:10.1093/bioinformatics/btn031
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© The Author (2008). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

TaxonGap: a visualisation tool for intra- and inter-species variation among individual biomarkers

B. Slabbinck 1,*, P. Dawyndt 2, M. Martens 3, P. De Vos 3 and B. De Baets 1

1KERMIT, Research Unit Knowledge-based Systems, Ghent University, Coupure links 653, 9000 Ghent, Belgium
1Department of Applied Mathematics and Computer Science, Ghent University, Krijgslaan 281 (S9), 9000 Ghent, Belgium
3Laboratory of Microbiology, Ghent University, K.L. Ledeganckstraat 35, 9000 Ghent, Belgium

*To whom correspondence should be addressed. Mr. Bram Slabbinck, E-mail: Bram.Slabbinck{at}UGent.be


  Abstract

Summary: Selection of optimal biomarkers for the identification of different operational taxonomic units (OTUs) may be a hard and tedious task, especially when phylogenetic trees for multiple genes need to be compared. With TaxonGap we present a novel and easy-to-handle software tool that allows visual comparison of the discriminative power of multiple biomarkers for a set of OTUs. The compact graphical output allows for easy comparison and selection of individual biomarkers.

Availability: Graphical User Interface; Executable JAVA archive file, source code, supplementary information and sample files can be downloaded from the website: http://www.kermit.ugent.be/taxongap.

Contact: Bram.Slabbinck{at}UGent.be, Peter.Dawyndt{at}UGent.be

Associate Editor: Prof. John Quackenbush

Received on November 6, 2007; revised on January 4, 2008; accepted on January 21, 2008

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