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Bioinformatics Advance Access published online on August 12, 2008
Bioinformatics, doi:10.1093/bioinformatics/btn427
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© The Author (2008). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

MPSQ: A web tool for protein state searching

Siyuan Zheng 1,2,{dagger}, Pei Hao 2,4,{dagger}, Jia Sheng 3, Chuan Wang 1, Yao Yu 1, Yun Li 1, Xiaojing Wang 1, Alex Michie 2, Jianliang Dai 2,4, Yang Zhong 4, Lei Liu 1,2,* and Yixue Li 1,2,3,*

1Bioinformatics Center, Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
2SCBIT-Inforsense Joint Lab, Shanghai Center for Bioinformation Technology, 100 Qinzhou Road, Shanghai 200235, China
3Life science and technology college of Shanghai Jiao tong University, Shanghai, China
4School of Life Sciences, Fudan University, Shanghai 200433, China

*To whom correspondence should be addressed. Lei Liu, Yixue Li, E-mail: liulei{at}scbit.org, yxli{at}sibs.ac.cn


  Abstract

Summary: MPSQ (Multi-Protein States Query) is a web based tool for the discovery of protein states. In particular, large sets of genes can be used to search for enriched state transition network maps and features facilitating the interpretation of genomic scale experiments such as microarrays. For the returned network map, graph visualization is provided for easy understanding and to guide further analysis.

Availability: MPSQ is freely available via the web at http://mpsq.biosino.org

Contact: liulei{at}scbit.org, yxli{at}sibs.ac.cn

Associate Editor: Dr.Jonathan Wren

{dagger}The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors

Received on May 22, 2008; revised on July 13, 2008; accepted on August 10, 2008

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