Bioinformatics Advance Access published online on October 7, 2008
Bioinformatics, doi:10.1093/bioinformatics/btn517
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CNVDetector: locating copy number variations using array CGH data
1Department of Computer Science and Information Engineering, 2Graduate Institute of Biomedical Electronics and Bioinformatics and 3Graduate Institute of Networking and Multimedia, National Taiwan University, Taipei, Taiwan
*To whom correspondence should be addressed. Prof. Kun-Mao Chao, E-mail: kmchao{at}csie.ntu.edu.tw
| Abstract |
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Summary: CNVDetector is a program for locating copy number variations in a single genome. CNVDetector has several merits: (1) it can deal with the array CGH data even if the noise is not normally distributed; (2) it has a linear time kernel; (3) its parameters can be easily selected; (4) it evaluates the statistical significance for each CNV calling.
Availability: CNVDetector (for Windows platform) can be downloaded from http://www.csie.ntu.edu.tw/~kmchao/tools/CNVDetector/.
Contact: kmchao{at}csie.ntu.edu.tw
Associate Editor: Dr. Alex Bateman
Received on March 12, 2008; revised on September 4, 2008; accepted on October 4, 2008
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