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Bioinformatics Advance Access published online on October 7, 2008

Bioinformatics, doi:10.1093/bioinformatics/btn517
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© The Author (2008). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

CNVDetector: locating copy number variations using array CGH data

Peng-An Chen 1, Hsiao-Fei Liu 1 and Kun-Mao Chao 1,2,3,*

1Department of Computer Science and Information Engineering, 2Graduate Institute of Biomedical Electronics and Bioinformatics and 3Graduate Institute of Networking and Multimedia, National Taiwan University, Taipei, Taiwan

*To whom correspondence should be addressed. Prof. Kun-Mao Chao, E-mail: kmchao{at}csie.ntu.edu.tw


   Abstract

Summary: CNVDetector is a program for locating copy number variations in a single genome. CNVDetector has several merits: (1) it can deal with the array CGH data even if the noise is not normally distributed; (2) it has a linear time kernel; (3) its parameters can be easily selected; (4) it evaluates the statistical significance for each CNV calling.

Availability: CNVDetector (for Windows platform) can be downloaded from http://www.csie.ntu.edu.tw/~kmchao/tools/CNVDetector/.

Contact: kmchao{at}csie.ntu.edu.tw

Associate Editor: Dr. Alex Bateman


Received on March 12, 2008; revised on September 4, 2008; accepted on October 4, 2008

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F.-C. Chen, Y.-Z. Chen, and T.-J. Chuang
CNVVdb: a database of copy number variations across vertebrate genomes
Bioinformatics, June 1, 2009; 25(11): 1419 - 1421.
[Abstract] [Full Text] [PDF]



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