Bioinformatics Advance Access published online on January 28, 2009
Bioinformatics, doi:10.1093/bioinformatics/btp045
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
QMSim: A large scale genome simulator for livestock
Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada
*To whom correspondence should be addressed. Dr. Mehdi Sargolzaei, E-mail: msargol{at}uoguelph.ca
| Abstract |
|---|
Summary: QMSim was designed to simulate large scale genotyping data in multiple and complex livestock pedigrees. The simulation is basically carried out in two steps. In a first step, a historical population is simulated to establish mutation-drift equilibrium and, in a second step, recent population structures are generated, which can be very complex. A wide variety of genome architectures, ranging from infinitesimal model to single locus model, can be simulated. The program is efficient in terms of computing time and memory requirements.
Availability: Executable versions of QMSim for Windows and Linux are freely available at http://www.aps.uoguelph.ca/~msargol/qmsim/.
Contact: msargol{at}uoguelph.ca
Associate Editor: Dr. Alex Bateman
Received on November 17, 2008; revised on January 15, 2009; accepted on January 18, 2009