Skip Navigation



Bioinformatics Advance Access published online on June 27, 2009
Bioinformatics, doi:10.1093/bioinformatics/btp398
This Article
Right arrow Advance Access manuscript (PDF) Freely available
Right arrowOA All Versions of this Article:
25/18/2447    most recent
btp398v1
Right arrow Comments: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Comments are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Google Scholar
Right arrow Articles by Stojmirovic, A.
Right arrow Articles by Yu, Y.-K.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Stojmirovic, A.
Right arrow Articles by Yu, Y.-K.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2009 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

ITM Probe: analyzing information flow in protein networks

Aleksandar Stojmirovic and Yi-Kuo Yu *

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, United States

*To whom correspondence should be addressed. Dr. Yi-Kuo Yu, E-mail: yyu{at}ncbi.nlm.nih.gov


  Abstract

Summary: Founded upon diffusion with damping, ITM Probe is an application for modelling information flow in protein interaction networks without prior restriction to the sub-network of interest. Given a context consisting of desired origins and destinations of information, ITM Probe returns the set of most relevant proteins with weights and a graphical representation of the corresponding sub-network. With a click, the user may send the resulting protein list for enrichment analysis to facilitate hypothesis formation or confirmation.

Availability: ITM Probe web service and documentation can be foundat www.ncbi.nlm.nih.gov/CBBresearch/qmbp/mn/itm_probe

Contact: yyu{at}ncbi.nlm.nih.gov

Associate Editor: Prof. Burkhard Rost

Received on April 21, 2009; revised on June 10, 2009; accepted on June 23, 2009

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.